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The original specimen appeared to have been tampered with (see § 40.65(c)(1)) or The temperature on the original specimen was out of range (see § 40.65(b)(5)) You observed materials brought to the collection site or the employee's conduct clearly indicates an attempt to tamper with a specimen (see §§ 40.61(f)(5)(i) and 40.63(e)) or You are directed by the DER to do so (see paragraph (a) of this section) or (c) As a collector, you must immediately conduct a collection under direct observation if: (b) As an employer, you must direct a collection under direct observation of an employee if the drug test is a return-to-duty test or a follow-up test. You realize a collection under direct observation was required but was not conducted or the service agent informs you that a direct observation should have been collected but was not (see paragraph (n) of this section). The laboratory reported to the MRO that the specimen was negative-dilute with a creatinine concentration greater than or equal to 2 mg/dL but less than or equal to 5 mg/dL, and the MRO reported the specimen to you as negative-dilute and that a second collection must take place under direct observation (see § 40.197(b)(1)). The MRO reported to you that the original positive, adulterated, or substituted result had to be cancelled because the test of the split specimen could not be performed or The laboratory reported to the MRO that a specimen is invalid, and the MRO reported to you that there was not an adequate medical explanation for the result (a) As an employer, you must direct an immediate collection under direct observation with no advance notice to the employee, if: § 40.67 When and how is a directly observed collection conducted?

Part 40 Federal Register Notices, Court Decisions, Legislation.Substance Abuse Professional Guidelines.DOT Agency / USCG Information & Regulations.49 CFR Part 40 (Drug and Alcohol Regulations).Breath Alcohol & Screening Test Technicians and Approved Devices.

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